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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEPT3
All Species:
17.58
Human Site:
T249
Identified Species:
32.22
UniProt:
Q9UH03
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UH03
NP_061979.3
358
40704
T249
D
E
D
L
E
D
K
T
E
N
D
K
I
R
Q
Chimpanzee
Pan troglodytes
Q5R1W1
434
50272
N231
E
T
D
D
E
E
E
N
K
L
V
K
K
I
K
Rhesus Macaque
Macaca mulatta
XP_001102088
360
40906
T251
D
E
D
L
E
D
K
T
E
N
D
K
I
R
Q
Dog
Lupus familis
XP_857693
357
40495
K248
F
D
E
D
L
E
D
K
T
E
N
D
K
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1S5
350
40019
T249
D
E
D
L
E
D
K
T
E
N
D
K
I
R
Q
Rat
Rattus norvegicus
Q9WU34
358
40579
T249
D
E
D
L
E
D
K
T
E
N
D
K
I
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505764
436
49083
R332
F
D
E
D
S
E
D
R
I
V
N
E
K
F
R
Chicken
Gallus gallus
Q5ZMH1
349
40206
S233
Q
T
R
V
L
K
A
S
I
P
F
A
V
I
G
Frog
Xenopus laevis
Q63ZQ1
352
40432
S233
Q
T
R
L
L
K
A
S
I
P
F
T
V
V
G
Zebra Danio
Brachydanio rerio
A2BGU8
361
40623
K260
F
D
E
D
M
E
D
K
S
D
N
D
K
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40797
539
60125
A329
L
E
D
A
A
E
E
A
K
T
T
Q
N
L
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795119
662
73144
T568
L
E
E
D
E
E
D
T
A
L
N
D
A
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25342
322
37006
I229
L
N
R
S
V
R
S
I
I
P
F
A
V
V
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.2
98.8
99.1
N.A.
94.1
98.5
N.A.
54.8
43.2
43.8
77
N.A.
31.1
N.A.
N.A.
34.1
Protein Similarity:
100
56.2
99.1
99.4
N.A.
94.9
99.1
N.A.
65.8
64.5
63.1
85.8
N.A.
45.2
N.A.
N.A.
42.6
P-Site Identity:
100
20
100
0
N.A.
100
100
N.A.
0
0
6.6
0
N.A.
13.3
N.A.
N.A.
20
P-Site Similarity:
100
53.3
100
33.3
N.A.
100
100
N.A.
40
20
20
40
N.A.
46.6
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
40.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
58.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
16
8
8
0
0
16
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
31
24
47
39
0
31
31
0
0
8
31
24
0
0
0
% D
% Glu:
8
47
31
0
47
47
16
0
31
8
0
8
0
0
0
% E
% Phe:
24
0
0
0
0
0
0
0
0
0
24
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
24
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
31
0
0
0
31
31
0
% I
% Lys:
0
0
0
0
0
16
31
16
16
0
0
39
31
0
8
% K
% Leu:
24
0
0
39
24
0
0
0
0
16
0
0
0
16
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
8
0
31
31
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
24
0
0
0
0
0
% P
% Gln:
16
0
0
0
0
0
0
0
0
0
0
8
0
0
31
% Q
% Arg:
0
0
24
0
0
8
0
8
0
0
0
0
0
31
39
% R
% Ser:
0
0
0
8
8
0
8
16
8
0
0
0
0
0
0
% S
% Thr:
0
24
0
0
0
0
0
39
8
8
8
8
0
0
0
% T
% Val:
0
0
0
8
8
0
0
0
0
8
8
0
24
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _